IgG subclasses, barrier function for albumin and production of immunoglobulin G in the central nervous system |
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| Authors: | Suad Al-Kassab Ph. D. Ludvig Dittmann Henrik Olesen |
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| Affiliation: | Department of Clinical Chemistry and Department of Neurology, Bispebjerg Hospital, Copenhagen, Denmark |
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| Abstract: | Cerebrospinal fluids from patients with neurological diseases have been studied. It appeared that the detectability of immunoglobulin G subclasses 1, 2, 3, 4, and the occurrence of oligoclonal bands in the IgG region increased with increasing concentration of IgG in the spinal fluid. No specific pattern emerged in the different disease groups. Formula: see text. |
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| Keywords: | Blood-brain barrier Sp-IgG subclasses 1, 2, 3, 4 oligoclonal bands reference intervals Sp-Albumin Sp-IgG S-Albumin/Sp-Albumin Sp-IgG × S-Albumin/S-IgG × Sp-Albumin neurological diseases cerebrospinal fluid |
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