| 维拉帕米缓释片与普萘洛尔防治偏头痛的比较 |
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| 引用本文： | 陈乃祥,崔荣华.维拉帕米缓释片与普萘洛尔防治偏头痛的比较[J].中国新药与临床杂志,1997(3). |
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| 作者姓名： | 陈乃祥 崔荣华 |
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| 作者单位： | 淮阴市第二人民医院(陈乃祥)，淮阴市城中人民医院(崔荣华) |
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| 摘 要： | 目的：比较维拉帕米缓释片与普萘洛尔对偏头痛的防治效果。方法：治疗组２６例（男性８例，女性１８例，年龄３３±ｓ５ａ），采用维拉帕米缓释片１２０ｍｇ，ｐｏ，ｑｄ，治疗６ｍｏ。对照组２６例（男性９例，女性１７例，年龄３３±７ａ），采用普萘洛尔片１０ｍｇ，ｐｏ，ｔｉｄ，递增至３０ｍｇ，ｔｉｄ，治疗６ｍｏ。结果：治疗组总有效率９２％，对照组总有效率６９％，经Ｒｉｄｉｔ分析统计，Ｐ＜０．０５。结论：维拉帕米缓释片防治偏头痛疗效优于普萘洛尔，不良反应轻微。
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| 关 键 词： | 偏头痛 维拉帕米 普萘洛尔 迟效制剂 |
Slow-release verapamil vs propranolol in preventing and treating migraine |
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| CHEN Nai-Xiang.Slow-release verapamil vs propranolol in preventing and treating migraine[J].Chinese Journal of New Drugs and Clinical Remedies,1997(3). |
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| Authors: | CHEN Nai-Xiang |
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| Abstract: | AIM: To compare the effects of slow-release verapamil and propranolol in preventing and treating migraine. METHODS: Treated group 26 patients (M 8, F 18, age 33±s 5 a) received slow-release verapamil tablet 120 mg, po, qd, for 6 mo; controlled group 26 patients (M 9, F 17, age 33±7 a) received propranolol tablet 10 mg, po, tid, gradually increased to 30 mg, po, tid, for 6 mo. RESULTS: The total effective rates were 92% in treated group and 69% in controlled group, respectively (P<0.05). CONCLUSION: The therapeutic effect of slow-release verapamil is superior to propranolol in preventing and treating migrain. Adverse reactions are mild. |
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| Keywords: | migraine verapamil propranolol delayed-action preparations |
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