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Association of hepatitis C virus infection and diabetes in central Tunisia
Authors:Naoufel Kaabia  Elhem Ben Jazia  Ines Slim  Imen Fodha  Wissem Hachfi  Rafika Gaha  Mabrouk Khalifa  Aoutef Hadj Kilani  Halim Trabelsi  Ahmed Abdelaziz  Fethi Bahri  Amel Letaief
Affiliation:Naoufel Kaabia;Elhem Ben Jazia;Ines Slim;Imen Fodha;Wissem Hachfi;Rafika Gaha;Mabrouk Khalifa;Aoutef Hadj Kilani;Halim Trabelsi;Ahmed Abdelaziz;Fethi Bahri;Amel Letaief
Abstract:AIM:To investigate hepatitis C virus (HCV) seroprevalence in Tunisian patients with diabetes mellitus and in a control group.METHODS:A crosssectional study was conducted to determine the HCV seroprevalence in 1269 patients with diabetes (452 male,817 female) and 1315 non diabetic patients,attending health centers in Sousse,Tunisia.HCV screening was performed in both groups using a fourthgeneration enzyme immunoassay.RESULTS:In the diabetic group,17 (1.3%) were found to be HCVinfected compared with eight (0.6%) in the control group,although the difference was not significant (P=0.057).Quantitative PCR was performed in 20 patients.Eleven patients were positive and showed HCV genotype 1b in all cases.CONCLUSION:Frequency of HCV antibodies was low in patients with diabetes and in the control group in central Tunisia,with no significant difference between the groups.
Keywords:Hepatitis C virus  Diabetes mellitus  Tunisia  Epidemiology  Autoantibodies  Hepatitis
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