非穿透性小梁手术联合丝裂霉素及深层巩膜反折疗效观察

目的:观察非穿透性小梁手术联合丝裂霉素及深层巩膜反折引流治疗开角型青光眼的临床效果。方法:对14例(18眼)开角型青光眼患者进行非穿透性小梁切除手术,术中联合应用丝裂霉素C及深层巩膜反折引流。观察手术前、后的眼压、视力、视野、前房(前房角)变化及手术后滤过泡情况。随访3~18mo。结果:术前平均眼压(33.96±8.16)mmHg(1mmHg=0.133kPa),术后眼压为(14.62±3.53)mmHg,手术前后眼压差异有显著意义(t=11.82,P<0.01)。手术前、后视力及视野无明显改变。术后16眼均形成滤过泡,其中I型6眼,Ⅱ型11眼,Ⅲ型1眼。结论:非穿透性小梁切除联合应用丝裂霉素及深层巩膜反折引流术是治疗开角型青光眼的一种安全、有效、便宜和具有可重复性的新治疗方式。

Curative effect observation of non-penetrating trabecular surgery combined with mitomycin C and deep sclera flap invagination

AIM: To observe and analyze the clinical effect of non-penetrating trabecular surgery combined with mitomycin C and deep sclera flap invagination in the treatment of open angle glaucoma.·METHODS: Fourteen cases (18 eyes) with open angle glaucoma were performed non-penetrating trabecular surgery combined with mitomycin C and deep sclera flap invagination. The vision acuity, visual field, intraocular pressure (IOP), anterior chamber (angle of anterior chamber) before and after operation, and filtering bleb after operation were observed. All patients were followed up for 3-18 months. ·RESULTS: The mean IOP before operation was (27.93±7.62)mmHg(1mmHg=0.133kpa), and (14.62±3.53)mmHg after operation, there was statistically significant diffe-rence between them (t=11.82,P<0.01). Vision acuity and visual field had no significant change after operation. All 16 eyes formed filtering bleb. Of the total, type filtering bleb was in 6 eyes, type in 11eyes and type in 1 eye. ·CONCLUSION:Non-penetrating trabecular surgery com-bined with mitomycin C and deep sclera flap invagination is a safe, effective, low cost and repeatable new treat-ment for open angle glaucoma.