高血压和合并动脉粥样硬化患者血小板分布宽度、血糖血脂水平变化及其危险因素分析

目的:回顾性比较高血压和合并动脉粥样硬化(AS)患者中血小板、血糖、血脂、血尿酸等指标的水平变化,分析高血压及合并AS的危险因子.方法:选取2019-06—2019-08在本院体检人群资料,按照检查结论分为高血压组(n=44)、高血压+AS组(n=73)和非高血压及AS对照组(n=91),采用临床检验科常规方法分别检测...

Changes of Platelet Distribution Width,Fasting Blood Glucose and Lipid Levels and Analysis of Risk Factors in Patients with Hypertension and Atherosclerosis

Objective:To analyze the changes of platelet distribution width(PDW),fasting blood glucose(FBG),blood lipid and blood uric acid in patients with hypertension and Atherosclerosis(AS),and the risk factors of hypertension and AS.Method:According to the conclusion of medical examination,the data of the population from June 2019 to August 2019 were selected and divided into hypertension group(n=44),hypertension+AS group(n=73)and non-hypertension and AS group(n=91)which is the control group.The platelet count(PLT),platelet distribution width(PDW),FBG,total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C)and blood uric acid(UA)in the three groups were detected by conventional methods in clinical laboratory.At the same time,statistical differences were compared between groups,and binary Logistics regression was performed on the index data with differences between groups to analyze their risk factors.Results:There were significant differences in PLT,PDW,FBG and LDL-C among the three groups(P<0.05),PLT in hypertension group and hypertension+AS group was lower than control group,and PDW in hypertension group and hypertension+AS group were higher than control group,the abnormality in hypertension+AS group was more obvious(P<0.05).The FBG in hypertension group and hypertension+AS group was significantly higher than that in control group,and the abnormality was more obvious in hypertension+AS group(P<0.05).The LDL-C in hypertension+AS group was significantly higher than that in hypertension group(P<0.05).Other indicators didn't show significant differences between groups(P>0.05).Conclusion:Patients with hypertension and hypertension+AS would have a higher platelet volume dispersion and higher levels of LDL-C and FBG which are the risk factors in the diseases above.