| Abstract: | Like strophanthin K, ethacrynic acid increases the sodium concentration and reduces the potassium concentration in frog urinary bladder tissue, with the result that potassium secretion is reduced; furosemide does not change these concentrations. The results point to differences in the intracellular action of furosemide and ethacrynic acid.Laboratory of Evolution of the Kidney and Water-Salt Metabolism, I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of the USSR, Leningrad. (Presented by Academician of the Academy of Medical Sciences of the USSR V. N. Chernigovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 9, pp. 319–321, September, 1977. |
