| 利福定固体分散物的制备及生物利用度测定 |
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| 引用本文： | 何仲贵, 唐星, 蔡玉珉. 利福定固体分散物的制备及生物利用度测定[J]. 中国现代应用药学, 1991, (2): 17-18. |
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| 作者姓名： | 何仲贵 唐星 蔡玉珉 |
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| 作者单位： | 沈阳药学院药剂教研室,沈阳药学院药剂教研室,沈阳药学院药剂教研室 沈阳市 110015,沈阳市 110015,沈阳市 110015 |
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| 摘 要： | 用溶媒法制备了利福定固体分散物。经X—射线衍射实验证明,利福定在固体分散物中呈无定形或以分子状态分散于载体中。固体分散物2小时的体外溶出量和人体生物利用度分别较原药提高了88%和21.8%。
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| 关 键 词： | 利福定 固体分散物 生物利用度 |
The Preparation and Determination of Bioavailability of Rifandin Solid Dispersion |
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| He Zhonggui, Tang xing, Cai Yumin. The Preparation and Determination of Bioavailability of Rifandin Solid Dispersion[J]. Chinese Journal of Modern Applied Pharmacy, 1991, (2): 17-18. |
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| Authors: | He Zhonggui Tang xing Cai Yumin |
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| Abstract: | Rifandin Solid Dispersion (RSD) were prepared by using "solvent method". Result showed that Rifandin (R) was dispersed in carrier with amorphous or molecularity through x-ray diffract experiment. The disolution amount of R in RSD was 88% more than that of |
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| Keywords: | Rifandin Solid dispersion Bioavailability |
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