| Survivin、p53蛋白在睾丸原发性非霍奇金淋巴瘤的表达及意义 |
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| 引用本文： | 梁群英,郭瑞珍,唐文台,肖庆邦.Survivin、p53蛋白在睾丸原发性非霍奇金淋巴瘤的表达及意义[J].贵州医药,2003,27(1):27-28,F002. |
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| 作者姓名： | 梁群英 郭瑞珍 唐文台 肖庆邦 |
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| 作者单位： | 遵义医学院病理教研室,563003 |
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| 摘 要： | 目的 探讨Survivin、p53蛋白在睾丸原发性非霍奇金淋巴瘤的表达及其意义。方法 对8例睾丸原发性非霍奇金淋巴瘤进行survivin,p53的免疫组化检测（S-P法）。结果 8例睾丸原发性非霍奇金淋巴瘤包括7例BCL和1例TCL；survivin阳性2例；p53阳性4例。结论 survivin和p53蛋白可能独立或协同作用地参与了睾丸原发性非霍奇金淋巴瘤中的发生发展。
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| 关 键 词： | 非霍奇金淋巴瘤 睾丸肿瘤 免疫组化 Survivin p53蛋白 |
Expression and significance of survivin and p53 protein in primary testicular non-Hodgkin's lymphoma |
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| Liang Qunying,Guo Ruizhen,Tang Wentai,et al..Expression and significance of survivin and p53 protein in primary testicular non-Hodgkin''''s lymphoma[J].Guizhou Medical Journal,2003,27(1):27-28,F002. |
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| Authors: | Liang Qunying Guo Ruizhen Tang Wentai |
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| Institution: | Liang Qunying,Guo Ruizhen,Tang Wentai,et al. Dept.of pathol,Zunyi Medical College,Zunyi 563003 |
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| Abstract: | Objective To explore the expression of survivin and p53 protein in primary testicular non-Hodgkin's lymphoma(NHL).Methods Survivin and p53 were detected in 8 cases of primary testicular NHL by immunohistochemical S-P method. Results 8 cases of primary testicular NHL included 7 cases of B-cell lymphoma and 1 case of T-cell lymphoma;2 case of primary testicular NHL were survivin positive and 4 cases were p53 positive. Conclusion The abnomal expression of survivin may be involved in the pathogenesis and progress of primary testicular NHL,independent of or in coopreation with p53 expression. |
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| Keywords: | Non-Hodgkin's lymphoma Testis |
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