| 白术挥发油β-环糊精包合物的工艺研究 |
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| 引用本文： | 葛亮,张志国.白术挥发油β-环糊精包合物的工艺研究[J].中国药业,2008,17(3):27-28. |
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| 作者姓名： | 葛亮 张志国 |
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| 作者单位： | 湖南中医药大学,湖南,长沙,410007 |
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| 摘 要： | 目的探索白术挥发油以β-环糊精包合的最佳工艺条件。方法以包合率和包合物产率为筛选指标，以挥发油与β-环糊精的配比、包合时间和包合温度为考察因素，采用正交试验对白术挥发油β-环糊精包合物的制备工艺进行优选。结果最佳工艺条件是挥发油与β-环糊精的配比为1：4，包合时间30min，包合温度30℃。结论优选出的工艺包合率和包合物产率均较高，工艺合理、可行。
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| 关 键 词： | 白术 挥发油 β-环糊精 包合物 正交设计 |
| 文章编号： | 1006-4931（2008）03-0027-02 |
| 收稿时间： | 2007-06-13 |
| 修稿时间： | 2007年6月13日 |
Study on β-cyclodextrin Inclusion Process of Volatile Oil from Atractylodes Rhizome |
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| Ge Liang,Zhang Zhiguo.Study on β-cyclodextrin Inclusion Process of Volatile Oil from Atractylodes Rhizome[J].China Pharmaceuticals,2008,17(3):27-28. |
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| Authors: | Ge Liang Zhang Zhiguo |
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| Institution: | (Hunan University of Traditional Chinese Medicine, Changsha, Hunan, China 410007) |
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| Abstract: | Objective To optimize the inclusion process for the volatile oil from Atractylodes Rhizome by β-cyclodextrin （CD）. Methods The process was studied by orthogonal experimental design using orthogonal form L9（3^4）, The utilization ratio of the volatile oil from Atractylodes Rhizome and the recovery ratio of inclusion compound were as criteria. And three factors were selected, including the ratio of the volatile oil to β- CD ,the time of preparation and the temperature, Results The optimal inclusion conditions were established as follows oil and β- CD（ 1：4）, the inclusion temperature and time were 30℃ and 30 min, respectively. Conclusion The optimized technology is reasonable and feasible with high inclusion rate and high receiving of inclusion. |
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| Keywords: | Atractylodes Rhizome volatile oil β-cyclodextrin inclusion compound orthogonal design |
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