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EDTA依赖性患者多种抗凝条件下血小板计数的比较分析
引用本文:巫小莉,周小棉,邓伟雄,邓穗德,张伟红,杨英为.EDTA依赖性患者多种抗凝条件下血小板计数的比较分析[J].广州医药,2007,38(6):47-49.
作者姓名:巫小莉  周小棉  邓伟雄  邓穗德  张伟红  杨英为
作者单位:广州市第一人民医院检验科,510180
摘    要:目的 观察EDTA依赖患者在多种抗凝条件下的血小板计数.方法 将已诊断为EDTA依赖患者的血置于多种抗凝条件(EDTA-K2、EDTA-Na2、枸橼酸钠、草酸钾-氟化钠、EDTAK2-氟化钠、EDTANa2-氟化钠、肝素锂),观察不同时间段内在血液分析仪上的血小板计数.结果 患者在多种抗凝条件下的血小板数随着时间的延长,均有不同程度的下降,观察血片均可见血小板聚集,属于罕见的多种抗凝剂依赖.结论 本例患者对多种抗凝剂依赖,其原因及机制有待进一步探讨.

关 键 词:EDTA依赖  抗凝剂  血小板
收稿时间:2007-10-20
修稿时间:2007年10月20

Comparative analysis of EDTA-dependent blood platelets count in a patient with different anticoagulants
Wu Xiaoli, Zhou Xiaomian, Deng Weixiong, et alh.Comparative analysis of EDTA-dependent blood platelets count in a patient with different anticoagulants[J].Guangzhou Medical Journal,2007,38(6):47-49.
Authors:Wu Xiaoli  Zhou Xiaomian  Deng Weixiong  h
Abstract:Objective To determine EDTA-dependent blood palatelets count in a patient with different anticoagulants. Methods Blood with different anticoagulants from the patient who has been diagnosed as EDTA-dependent were analyzed by the blood analyzer and platelets count in different interval was recorded. The anticoagulants used in this study included EDTA- K2, EDTA-Na2, sodium citrate, postassium oxalate-NaF, EDTA-K2-NaF, EDTA-Na2-NaF and hepafin lithiumj. Results As time passed, platelets count in the blood with different anticoagulants decreased respectively. Platelet aggregations were also observed on the blood smears. Conclusions This patient is one of scarce cases with multi-anticoagulants dependent. The mechanism of EDTA-dependence in the case will be further studied.
Keywords:EDTA-dependent  Anticoagulant  Blood platelet
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