Interstitial lung disease as the first manifestation of systemic sclerosis |
| |
Authors: | van der Kamp R Tak P P Jansen H M Bresser P |
| |
Institution: | Department of Pulmonology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. |
| |
Abstract: | We describe three patients with progressive fibrosing interstitial lung disease (ILD) as the first and only manifestation of systemic sclerosis. In one patient the presence of anti-Scl-70 autoantibodies suggested systemic sclerosis to be the underlying cause of the disease. In the two other subjects, however, anti-Scl-70 antibodies were negative. In these patients the lung disease preceded other manifestations of systemic sclerosis by several years. Diagnosis, prognosis and treatment of systemic sclerosisassociated ILD is discussed. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|