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| HPLC法测定冠心康颗粒中芍药苷的含量 | |
| 引用本文： | 郑建锋,郑阿利,盖轲. HPLC法测定冠心康颗粒中芍药苷的含量[J]. 中国药事, 2011, 25(4): 377-378,381 |
| 作者姓名： | 郑建锋 郑阿利 盖轲 |
| 作者单位： | 1. 甘肃省西峰制药有限责任公司,庆阳,745000 2. 甘肃省庆阳市药品检验所 3. 甘肃省陇东学院化学化工学院 |
| 摘 要： | 目的建立以HPLC法测定冠心康颗粒中芍药苷含量的方法。方法采用phenomenex luna C18色谱柱;流动相:甲醇-水(27∶73);流速:0.8mL.min-1;检测波长:230nm;柱温:30℃。结果芍药苷在6.029~60.29μg.mL-1范围内线性关系良好,r=0.9999,平均回收率为99.53%,RSD为0.79%。结论该方法简便、可行,重复性好,可作为冠心康颗粒的质量控制方法。 |
| 关 键 词： | 芍药苷 冠心康颗粒 HPLC |
Determination of Paeoniflorin in Guanxinkang Granules by HPLC |
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| Zheng Jianfeng,Zheng Ali,Gai Ke. Determination of Paeoniflorin in Guanxinkang Granules by HPLC[J]. Chinese Pharmaceutical Affairs, 2011, 25(4): 377-378,381 | |
| Authors: | Zheng Jianfeng Zheng Ali Gai Ke |
| Affiliation: | Zheng Jianfeng,Zheng Ali1 and Gai Ke2(Gansu Xifeng Pharmaceutical Co.,Ltd,Qingyang 745000,1Qingyang City Institute for Drug Control,Gansu province,2Gansu Provincial Longdong Institute of Chemistry and Chemical Engineering) |
| Abstract: | Objective To establish a HPLC method to determine the content of paeoniflorin in Guanxinkang Granules.Methods Phenomenex luna C18 column was used as chromatographic column.The mobile phase was methanol-water（27∶73）.The flow rate was 0.8mL·min-1,and detection wavelength was at 230nm.The column temperature was 30℃.Results The good linear range of paeoniflorin was 6.029~60.29μg·mL-1,r=0.9999.The average recovery was 99.53%,RSD=0.79%.Conclusion The method is simple,feasible and reproducible.It can be used for the quality control of Guanxinkang Granules. |
| Keywords: | HPLC |
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