低频重复电刺激检查在重症肌无力诊断中的临床意义

目的 探讨低频重复电刺激(RNS)检查在重症肌无力(MG)患者中的诊断作用.方法 回顾性分析2008年7月至2010年8月住院确诊436例MG患者低频RNS的检查结果,分析MG患者中低频RNS阳性率,不同受榆肌群及MG各临床分型低频RNS异常率.结果 MG患者中低频RNS阳性率为73.85%.低频RNS异常以刺激面神经...

Clinical value of low-frequency repetitive nerve stimulation in myasthenia gravis

Objective To explore the value of low-frequency repetitive nerve stimulationRNSin the diagnosis of myasthenia gravisMG.Methods A total of 436 MG patients admitted during the period of July 2008 and August 2010 and undergoing the repetitive nerve stimulation test were reviewed retrospectivelv.We analyzed the positive rates of RNS in MG patients and compared the abnormalities in different nerves including facial,accessory.axillary and ulnar nerves.Results Among them,73.85% had abnornlal recordings on low-frequency RNS test.The highest abnormality was in facial nerves82.30%,then axillary nerves52.17%and the lowest in ulnar nerves27.64%.The positive rates of RNS in ocular MG were significant lower than those in general MG patients.And there were no significant statistical differences of RNS abnormalrates in types Ⅱ a,Ⅱb,Ⅲ and Ⅳ MG patients with 89.66%,82.56%,91.67%and 83.33%,respectively.In ocular MG,16.34% patients were positive in RNS test under the stimulation of accessory.axillary and ulnar nerves.And 79.50%patients with general MG had two or more nerves with abnormal results.Conclusion The low-frequency RNS test is of great value in the diagnosis of MG.And it shows a higher sensitivity in general MG patients than that in ocular ones.The stimulation of facial and axillary nerves increases the positive rates of RNS in MG patients.