| 臭参补气生血的药效研究 |
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| 引用本文： | 陈子珺,李云森,鲁岚,陆宾,周吉燕,胡月娟. 臭参补气生血的药效研究[J]. 上海中医药杂志, 2009, 43(2): 68-71 |
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| 作者姓名： | 陈子珺 李云森 鲁岚 陆宾 周吉燕 胡月娟 |
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| 作者单位： | 上海中医药大学中药研究所药理二室,上海,201203;中国科学院上海生命科学研究院上海药物研究所新药研究国家重点实验室,上海,201203 |
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| 基金项目： | 上海市教育委员会资助项目 |
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| 摘 要： | 目的探讨臭参水提液和醇提液补气生血的作用。方法以饥饿法复制小鼠气虚动物模型,乙酰苯肼(APH)和环磷酰胺(CTX)联合注射复制小鼠血虚模型。观察臭参水提液和醇提液补气生血的作用。结果臭参醇提液高、低剂量组均能明显升高气虚小鼠负重游泳后的血糖,可明显升高血虚小鼠的体温;醇提液高剂量组还能明显延长气虚和血虚小鼠负重游泳时间,增加气虚小鼠的胸腺指数;醇提液低剂量组还能升高血虚小鼠的白细胞。臭参水提液高、低剂量组均能明显升高气虚小鼠负重游泳后血糖;水提液高剂量组还能明显升高气虚小鼠负重游泳后的尿素氮,增加气虚和血虚小鼠的脾脏指数;水提液低剂量组还能增加气虚小鼠的胸腺指数。结论臭参醇提液具有明显的补气生血作用,水提液则具有一定的抗疲劳和增强免疫作用。
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| 关 键 词： | 臭参 气虚模型 血虚模型 补气生血 |
Pharmacodynamic Study on Qi-Blood-Enriching Effects of Codonopis Bulleynana Forest ex Diels |
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| CHEN Zi-jun LI Yun-sen LU Lan LU Bing ZHOU Ji-yan HU Yue-juan. Pharmacodynamic Study on Qi-Blood-Enriching Effects of Codonopis Bulleynana Forest ex Diels[J]. Shanghai Journal of Traditional Chinese Medicine, 2009, 43(2): 68-71 |
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| Authors: | CHEN Zi-jun LI Yun-sen LU Lan LU Bing ZHOU Ji-yan HU Yue-juan |
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| Affiliation: | CHEN Zi-jun1 LI Yun-sen2 LU Lan1 LU Bing1 ZHOU Ji-yan1 HU Yue-juan1 1.Institute of Chinese Meteria Medica,Shanghai University of Traditional Chinese Medicine2.Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences |
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| Abstract: | Objective To study the qi-blood-enriching effects of water and alcohol extracts of Codonopis Bulleynana Forest ex Diels.Methods Qi-deficiency model and blood-deficiency model of mice were induced by starvation and acelyphenylhydrazine(APH)and cyclophosphamide(CTX)respectively.Results High-and low-dose groups of alcohol extract of Codonopis Bulleynana Forest ex Diels(HA/LA)obviously increased blood glucose of qi-deficiency mice after swimming,raised the body temperature of blood-deficiency mice.HA significan... |
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| Keywords: | Codonopis Bulleynana Forest ex Diels qi-deficiency model blood-deficiency model enriching qi and blood |
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