| Hypertonic saline solution resuscitation in hemorrhagic shock dogs |
| |
| 引用本文： | 蔡秀军,黄迪宇,牟一平,彭淑牖. Hypertonic saline solution resuscitation in hemorrhagic shock dogs[J]. 中华创伤杂志(英文版), 2002, 5(3): 180-185 |
| |
| 作者姓名： | 蔡秀军 黄迪宇 牟一平 彭淑牖 |
| |
| 作者单位： | DepartmentofGeneralSurgery,SirRunRunShawHospital,ZhejiangUniversity,Hangzhou310016,China |
| |
| 摘 要： | Objective: To find out the optimal concentration,infusion rate and dosage of saline for resuscitation. Methods: Forty-five dogs were used to establish hypovolemic shock models. The dogs were resuscitated with saline of different concentrations and different dosages under different infusion rates, and the resuscitation results were compared. Results: The best concentration was 7.5%, the best rate of infusion 20 ml/min ( a volume equivalent to 15 % of the shed blood ) and the best dosage 5.71 ml/kg. The method was effective for resuscitation, the mean arterial pressure (MAP) could be elevated to 89 % of the baseline,and this MAP could be kept for more than one hour. Conclusions： Using 7.5% sodium chloride solution equivalent to 15% of the shed blood at an infusion rate of 20 ml/min can achieve a best resuscitation result.
|
| 关 键 词： | 高渗盐 失血性休克 狗类 动物试验 剂量 灌注速率 |
Hypertonic saline solution resuscitation in hemorrhagic shock dogs |
| |
| Xiujun Cai,Diyu Huang,Yiping Mu,Shuyou Peng. Hypertonic saline solution resuscitation in hemorrhagic shock dogs[J]. Chinese journal of traumatology, 2002, 5(3): 180-185 |
| |
| Authors: | Xiujun Cai Diyu Huang Yiping Mu Shuyou Peng |
| |
| Affiliation: | Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China |
| |
| Abstract: | OBJECTIVE: To find out the optimal concentration, infusion rate and dosage of saline for resuscitation. METHODS: Forty-five dogs were used to establish hypovolemic shock models. The dogs were resuscitated with saline of different concentrations and different dosages under different infusion rates, and the resuscitation results were compared. RESULTS: The best concentration was 7.5%, the best rate of infusion 20 ml/min (a volume equivalent to 15% of the shed blood) and the best dosage 5.71 ml/kg. The method was effective for resuscitation, the mean arterial pressure (MAP) could be elevated to 89% of the baseline, and this MAP could be kept for more than one hour. CONCLUSIONS: Using 7.5% sodium chloride solution equivalent to 15% of the shed blood at an infusion rate of 20 ml/min can achieve a best resuscitation result. |
| |
| Keywords: | Shock,hemorrhagic Saline solution,hypertonic Dogs |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
