膳食纤维不同成分对大鼠脂质代谢的影响

本文观察了3种不同膳食纤维(DF)制成品(纤维素、果胶、琼脂)对高胆固醇膳大鼠脂质代谢的影响。结果发现:果胶和纤维素组自实验2周末,琼脂组于6周末与对照组相比有明显的降低血清TC作用;3种DF均有不同程度降低肝胆固醇作用;各组血清TG、HDL-C,HDL_2-C,HDL_3-C间无显著差异;纤维素组和果胶组HDL-C/TC比值明显高于对照组。3种DF均可使大鼠排粪量增加,对大鼠摄食量及生长无影响。

THE EFFECTS OF CELLULOSE, PECTIN AND AGAR ON LIPID METABOLISM IN RATS FED A HIGH CHOLESTEROL DIET

This paper was designed to study the effects of cellulose, pectin and ag-ar at 10% level on the concentration of serum total cholesterol (TC), trigly-ceride (TG) and high density lipoprotein cholesterol (HDL-C) in rats. Male adult Wistar rats were randomly divided into 5 groups and fed on basal diet, hypercholesterolemic diet (control diet) and 3 test diets (contain 10% cellulose, pectin or agar respectively) for 6 weeks. The results showed that all three fibrous diets were significantly lowered serum TC (P<0.01) and liver TC (P<0.01)to compare with the control group, pectin being the most effective. TG and HDL-C level were not significantly altered by the three kinds of fibers. HDL-C/TC value in cellulose and pectin groups were significantly higher than that of control group, i.e., cellulose and pectin could relatively increase HDL-C. It generally considered that the decreased value of HDL-C/TC is a risk factor of coronary heart disease (CHD). From this point of view, cellulose and pectin may have some protective effect on CHD.The paper also showed that the kinds of fibers concerned could increase the bulk of stool, but didn't affect the dietary intake and weight gain of rats.