三个时期糖尿病视网膜病变多焦视网膜电图的差异

目的研究三个时期糖尿病视网膜病变的多焦视网膜电图特征及其临床意义。方法采用VERISⅣ视觉诱发反应图像系统测量和分析了34例非增殖期、15例增殖前期和15例增殖期糖尿病视网膜病变的多焦视网膜电图的差异。结果与正常对照眼比较，增殖期糖尿病视网膜病变，多焦视网膜电图的N

Variation of multifocal electroretinograms in different stages of diabetic retinopathy

To investigate the characteristics of the multifocal electroretinograms in non-proliferative, severe nonproliferative and proliferative stages of diabetic retinopathy (DR), sixty-four patients with DR were studied, of which 34 were in non-proliferative stage, 15 were in severe nonproliferative stage and 15 were in proliferative stage. The multifocal electroretinograms of the eyes with DR in the three stages were tested with VERIS IV system. In proliferative stages of DR, the latencies of N1, P1 and N2 components were prolonged in the field of 45 degrees in diameter; in severe nonproliferative stages of DR, the latencies of P1 and N2 components were prolonged in the ring band from 10.5° to 22.5° eccentricity; and in non-proliferative, severe nonproliferative and proliferative stages, the N1-P1 and P1-N2 response densities (amplitude/area) were attenuated in the field of 45 degrees in diameter. In conclusions, the latency and the response density of multifocal electroretinograms have different sensitivity in detecting the dysfunction of retina in different stages of DR；the response density is more sensitive than the latency in detection of early DR.