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大鼠实验性胃溃疡自愈过程中血浆ACTH放射免疫测定的研究
引用本文:苏宇华,石爱荣. 大鼠实验性胃溃疡自愈过程中血浆ACTH放射免疫测定的研究[J]. 北京大学学报(医学版), 1991, 0(4)
作者姓名:苏宇华  石爱荣
作者单位:北京医科大学组织学胚胎学教研室,北京医科大学组织学胚胎学教研室
摘    要:为研究垂体ACTH细胞在胃溃疡自愈过程中的可能作用,本实验用放射免疫法测定大鼠实验性胃溃疡不同时期血浆ACTH水平的变化。结果表明,实验动物在术后6天,ACTH水平明显高于对照组,术后10天仍保持高水平。ACTH水平的升高发生于溃疡愈合期,提示ACTH在溃疡愈合中起有益的作用。

关 键 词:胃溃疡  促肾上腺皮质激素  放射免疫测定

RADIOIMMUNOASSAY OF PLASMA ACTH LEVEL DURING HEALING PROXESS OF EXPERIMENTAL GASTRIC ULCER IN RAT
Su Yuhua,Shi Airong Deparment of Histology and Embryology. RADIOIMMUNOASSAY OF PLASMA ACTH LEVEL DURING HEALING PROXESS OF EXPERIMENTAL GASTRIC ULCER IN RAT[J]. Journal of Peking University. Health sciences, 1991, 0(4)
Authors:Su Yuhua  Shi Airong Deparment of Histology  Embryology
Affiliation:Su Yuhua;Shi Airong Deparment of Histology and Embryology
Abstract:The plasma ACTH levels during the experimental gastric ulcer of the rats were measured by radi-oimmunoassay, in ordet to investigate the role of corticotrophs in the healing of gastric ulcer. Theresults showed that the plasma ACTH level of experimental group rose to the highest value on thesixth day and maintained at higher level to the tenth day after the operation. Elevation of plasmaACTH concentration coincided with the period when the ulcers began repairing, which supports the ass-umption that ACTH played some beaeficial role in experimental gastric ulcer healing.
Keywords:Gastric ulcer  ACTH  Radioimmunoassay
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