| 玉米活性肽对辐射防护作用的研究 |
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| 引用本文： | 王玲,宋淑珍,田亚平. 玉米活性肽对辐射防护作用的研究[J]. 军医进修学院学报, 2005, 26(5): 340-341 |
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| 作者姓名： | 王玲 宋淑珍 田亚平 |
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| 作者单位： | 解放军总医院,生化科,北京,100853 |
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| 摘 要： | 目的:观察玉米活性肽对X线照射正常机体造血功能的保护作用。方法:观察20只NIH小鼠按对照组(正常饲料)、给药组(含玉米活性肽30g/100g饲料)进行照射3d后血象的改变(能量6mVX线,剂量6Gy,面积30 cm×30 cm),和2周后血象的恢复情况。结果:放疗后与放疗前比较,3d后对照组与给药组的白细胞均明放疗后与放疗前比较,3d后对照组与给药组的白细胞均明显降低,并且MDA升高,SOD活性下降。2周后与放疗前比较,SOD活性恢复,MDA降低,给药组与对照组白细胞数得到恢复,给药组白细胞增加明显,与对照组差异显著(P<0.05)。血色素水平于照后3d变化不大,14d后降低明显。试验组与对照组无差别。血小板在照后3d时无明显变化,但2周后下降明显,给药组高于对照组(P<0.05)。结论:玉米活性肽可能通过提高小鼠抗氧化水平,对X线照射小鼠造血功能具有防护作用。
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| 关 键 词： | 玉米 活性肽 辐射防护作用 造血功能 抗氧化能力 |
| 文章编号： | 1005-1139（2005）05-0340-02 |
| 收稿时间： | 2005-02-16 |
| 修稿时间： | 2005-03-10 |
The protective effects of nanometer corn activity peptides against X-ray induced damage on mice |
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| WANG Ling,SONG Shu-zhen,TIAN Ya-ping. The protective effects of nanometer corn activity peptides against X-ray induced damage on mice[J]. Academic Journal of Pla Postgraduate Medical School, 2005, 26(5): 340-341 |
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| Authors: | WANG Ling SONG Shu-zhen TIAN Ya-ping |
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| Abstract: | Objective:To assess the protective effect of corn activity peptides against X-ray induced damage on mice.(Methods:20) NIH mice were randomly divided into two groups in modifying the radiation-induced leukopenia.Results:leukopenia induced by X-ray can be inhibited by corn activity peptides on mice,also be got a fast recovery.Conclusion:our findings indicated that corn activity peptides may have therapeutic value as a possible radioprotector for normal tissue during radiotherapy of cancer patients |
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| Keywords: | X-ray mice corn |
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