Cronkhite-Canada综合征一例并文献复习

目的记录并报道Cronkhite—Canada综合征1例，以加强对本病的认识。方法搜集患者的临床资料，包括症状、体征及辅助检查，查阅相关文献，尝试各种治疗方法。结果患者符合Crankhite—Canada综合征，普通的中西止泻药物无效，激素治疗有效。结论Cronkhite—Canada综合征患者为非家族性，镜下特点为多发胃肠道息肉，以腹泻为主要症状并伴有外胚层改变。普通止泻药物无效，可尝试激素治疗。

Cronkhite-canada syndrome:a case report and review of literature

Objective To improve the recognition of Cronkhite-Canada syndrome （CCS） by reporting a case. Methods Collect the data of the patient,including the clinical feature, sign and the labo- ratory examination, review the related literatures, and try several therapies. Results The patient was con- sistant with CCS, and no ordinary antidiarrhea drugs but glucocorticosteroids are effective. Conclusions CCS is a rare non-familial syndrome, which is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation and diarrhea, commom antidiarrhea drugs is ineffective. ,and man can try glucocorticosteroids therapy.