急性心肌梗死并泵衰竭早期应用主动脉内球囊反搏对心功能的影响

目的评价急性心肌梗死(AMI)并泵衰竭的患者早期应用主动脉球囊反搏术(IABP)对心功能的影响。方法选取AMI并泵衰竭、入院后6h内无心源性休克发生的患者共计54例,其中IABP组27例,在直接PCI、积极药物治疗基础上早期应用IABP辅助治疗;对照组27例,给予直接PCI及积极药物治疗,若病情进展至心源性休克,则给予IABP治疗。比较两组患者住院24h内及发病后随访6月时超声心动图及血浆BNP水平。结果 IABP组与对照组24h内纽约心功能分级、左心室功能指标及血浆BNP水平无显著差异(P﹥0.05),但发病6月IABP组BNP水平显著低于对照组(P﹤0.05),超声心动图示左心室功能指标IABP组显著优于对照组(P﹤0.05)。结论早期应用IABP能显著改善AMI并泵衰竭患者心功能。

Effect of early usage of intra-aortic balloonpump on cardiac function in patients

【Objective】To investigate the effect of early usage of intra-aortic balloonpump(IABP) on cardiac function in patients with acute myocardial infarction(AMI) complicated by pump failure.【Methods】 54 patients with AMI complicated by pump failure underwent primary PCI were randomly divided into two groups: the IABP group(N=27) received early IABP support and the control group(N=27) received IABP support only when aggravated to cardiac shock.The ultrasonic indexes and the serum BNP level were measured after 24 hours and 6 months after admitted.【Results】 The ultrasonic indexes or the serum BNP level did not show significant differences between the two groups 24 hours after admitted(P>0.05).However,at sixth month,compared with control group,the IABP group showed significantly improved unltrasonic indexes and the serum BNP level(P<0.05).【Conclusion】 Early usage of intra-aortic balloonpump(IABP) improved cardiac function in patients with acute myocardial infarction(AMI) complicated by pump failure.