小剂量阿托品预防PCI后拔除股动脉鞘管所致迷走反射疗效分析

目的 探讨经皮冠状动脉介入治疗术后拔除股动脉鞘管所致迷走反射的预防方法。方法经皮冠状动脉介入治疗术后患者500例．预防组242例．对照组258例。两组拔管前均给予生理盐水100—150ml／h，应用4h，拔管时2％利多卡网鞘管周同浸润麻醉；预防组拔管前静椎阿托品05mg，其余同对照组。结果预防组发生迷走反射0例，对照组发生6例，两组比较，差异具有统计学意义（P〈0．05）。结论经皮冠状动脉介入治疗术后，应用小剂量阿托品可以预防拔除股动脉鞘管所致的迷走反射。

Low -dose atropine prevent the vagal reaction induced by removing femoral artery sheath after PCI

Objective To investigate the prophylaxis of vagal reaction induced by removing femoral artery sheath after percutaneous coronary intervention （ PCI）. Methods 500 cases after PCI were observed, they were divided randomly into prevention group （242 cases） and control group （258 cases）, in the control group, 100 -150 ml/h saline was given, lasting 4 hours before removing femoral artery sheath, and infiltration of 2 percent lidocaine was used to anesthetize beside the sheath when removing; in prevent group, we use the same treatment of the control group and 0. 5 mg atropine before removing femoral artery sheath. Results None of the prevention group presented vagal reaction, but 6 cases did in the control group. There were significantly difference between the two groups （ P 〈 0.05 ）. Conclusion The low - dose atropine could prevent the vagal reaction induced by removing femoral artery sheath after PCI.