康艾注射液对人结直肠癌Lovo细胞Th1/Th2类细胞因子的影响 |
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引用本文: | 刘季芳,祁岩超,卢敏莹,潘东晓,申鸿卓. 康艾注射液对人结直肠癌Lovo细胞Th1/Th2类细胞因子的影响[J]. 国际医药卫生导报, 2005, 15(23): 24-26. DOI: 10.3760/cma.j.issn.1007-1245.2009.14.008 |
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作者姓名: | 刘季芳 祁岩超 卢敏莹 潘东晓 申鸿卓 |
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作者单位: | 广州医学院附属肿瘤医院,510095; |
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摘 要: | Objective To explore the effect of Kang'ai injection on Th1/Th2 cytokine in human colon carcinoma cell line Lovo.Methods Lovo cells were cultured by conventional ways until they were in exponential growth phase and then divided into 4 groups:one control group and three experimental groups with different concentration of Kang'ai injection.After 72 hours culture,Th1 type cytokines (IL-2,IFN-γ) and Th2.type cytokines (IL-4,IL-10) in the culture supernatant of Lovo cells in each group were separately detected by double-antibody sandwich enzyme-linked immunosorhent assay (ELISA).Results After the coculture of Lovo cells and Kang'ai injection,Th2 type cytokine levels in the supernatants were significant lower than the control group (P<0.05),and Th1 type cytokines in each group were of little change.Conclusions Kang'ai injection markedly downregulated Th2 type cytokines in Lovo cells,and contributed to the switching from Th2 to Th1.
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关 键 词: | 康艾注射液 逆转 免疫治疗 |
Effect of Kang'ai Injection on Th1/Th2 cytokines in human colon carcinoma cell line Lovo |
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Abstract: | |
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Keywords: | Th1/Th2Kang'ai injectionTh1/Th2ReversionImmunotherapy |
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