2-型糖尿病对冠状动脉病变影响的分析

目的探讨2-型糖尿病(T2DM)对冠状动脉病变的影响。方法回顾性分析近4年492例选择性冠状动脉造影的住院病例,比较T2DM与非糖尿病患者冠状动脉病变的特点,包括病变程度、累及的血管数目。结果与非糖尿病组比较,T2DM组冠状动脉发生病变更多见(P<0.01),左回旋支(LCX)、右冠状动脉(RCA)发生病变的比例高于非糖尿病组(均P<0.01),T2DM组3支血管均发生病变的比例显著增高(P<0.01));经协方差分析,T2DM组与非糖尿病组在冠状动脉病变的程度上存在显著差异(F=2.56,P=0.001),在累及血管的数目上亦存在有统计学意义的差异(F=2.109,P=0.011)。结论T2DM患者更容易发生冠状动脉病变,且冠状动脉病变的程度较重、受累及的血管数目较多。

Effect of 2-diabetes mellitus on coronary artery disease

Objective Toobserve the effect of 2-diabetes mellitus (2-DM) on coronary artery disease. Methods 492 hospitalizd patients underwent a selective coronary angiography during the past 4 years were analyzed, and compare the characteristic of coronary artery disease,the severity of lesion and the number of lesion vessels in 2-DM groups with nondiabetic groups. Results In 2-DM groups,the rat of coronary disease increased significantly (P<0.01),abnormal LCX and RCA were found more frequently (P<0.01), and three-vessel disease was higher (P<0.01). By analysis of corariance,the results show that there was highly significant differences between 2-DM groups and nondiabetic groups in severity of lesion (F=2.56, P=0.001) and there was statistical significant differences in the number of lesion vessel(F=2.109, P=0.011). Conclusion Patients with 2-DM is susceptibility to coronary artery disease,usually is associated with more severity of lesion and more lesion vessel.