Response of rat exocrine pancreas to chronic pulmonary ethanol intoxication |
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| Authors: | J. Chariot PhD B. Le Bourhis PhD Dr. C. Rozé MD PhD F. Potet MD |
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| Affiliation: | (1) Laboratoire de Biologie et Physiologie des Cellules Digestives (FRA 49 INSERM), Faculté de Médecine X. Bichat, 16 rue H. Huchard, 75018 Paris, France;(2) Institut de Recherches Appliquées aux Boissons, 120 avenue Foch, 94015 Creteil, France |
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| Abstract: | Rats were intoxicated over a 32-day period by continuous exposure to an ethanol-enriched atmosphere. Under these conditions, body weights increased up to day 26 and blood ethanol levels increased to approximately 2 g/liter. Pancreatic and hepatic histologies were normal. Amylase levels and total pancreatic protein decreased, while lipase levels rose. These changes appear to be independent of the caloric balance of the diet. |
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