前列腺癌穿刺活检的误诊分析

随着临床上B超引导下前列腺穿刺活检的开展，前列腺癌的病理诊断中遇到了一些困难．本文收集解放军总医院1980年～1993年间前列腺穿刺活检397例中原诊断前列腺癌的142例，重新复片，发现14例非癌．同时在前列腺增生中发现7例为癌，最后确诊为前列腺癌135例．分析误诊的因素后发现过失诊断的情况是将增生、萎缩、炎细胞、人为挤压四种因素误认为是癌，反之，诊断不足的情况是将高分化癌、导管内癌、癌间质增生、未分化小细胞癌四种因素误认为非癌。上述结果对于提高前列腺活检标本中前列腺癌的诊断有一定意义．

Diagnosis of Prostatic Carcinoma by Aspiration Biopsy: An Analysis of Misdiagnostic Causes

As the wide appplication of aspiration biopey guided by u lt rasonography, which provides a tiny bit of tissue for pat holth gists,have make it more difficult for pathoIogic diagnosis. This papbr deals with the probIems of histopathological over and under-diagnoris of prostatic carcinomas. From 1980~1993,there were 397 cases with aspisation bioPSy. The initiate diagnosis of proatatic carcinoma was l42 cases. After the HE stain s1ides reviewed, l4 cases were not carcinoma. In the cases of prostatic proliferation, 7 cases with cancer was found. The final diagnosis with prortatic carcinoma was 135 cases. Hyperplasia, atrophy, inflammation, and tissue squashed were the causes for the over-diagneds. Carcinomas with well-differentiation, intraductal,amall cell,and stromal reaction were the causes for the under-diagneds. We bekeve that the recognition of thase misdiagnostic cases will be valuable for the pathologic diagnosis of prostatic carcinomas.