| 桦木酸和2,3-羟基桦木酸抗肿瘤作用机制的研究进展 |
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| 引用本文： | 张晶,张秀娟,凌莉莉. 桦木酸和2,3-羟基桦木酸抗肿瘤作用机制的研究进展[J]. 亚太传统医药, 2008, 4(1): 62-64 |
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| 作者姓名： | 张晶 张秀娟 凌莉莉 |
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| 作者单位： | 哈尔滨商业大学生命科学与环境科学研究发展中心,黑龙江,哈尔滨,150076 |
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| 基金项目： | 哈尔滨商业大学研究生创新基金项目;黑龙江省自然科学基金项目（C200604）. |
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| 摘 要： | 桦木酸和2,3-羟基桦木酸均是羽扇豆烷型五环三萜类化合物,具有多方面的药理活性,其抗肿瘤作用近年来受到了极大的关注。目前,国内外关于桦木酸和2,3-羟基桦木酸抗肿瘤作用的研究表明,桦木酸和2,3-羟基桦木酸可通过抑制肿瘤细胞增殖、转移,诱导肿瘤细胞分化和凋亡,从而起到抗肿瘤的作用。
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| 关 键 词： | 桦木酸 2,3-羟基桦木酸 抗肿瘤 |
| 文章编号： | 1673-2197（2008）01-062-03 |
| 收稿时间： | 2007-11-06 |
Study Progress of Anti-tumor Mechanism of Betulinic Acid and 2,3-hydroxyl Betulinic Acid |
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| Zhang Jing,Zhang Xiujuan,Ling Lili. Study Progress of Anti-tumor Mechanism of Betulinic Acid and 2,3-hydroxyl Betulinic Acid[J]. Asia-Pacific Traditional Medicine, 2008, 4(1): 62-64 |
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| Authors: | Zhang Jing Zhang Xiujuan Ling Lili |
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| Affiliation: | Zhang Jing, Zhang Xiujuan, Ling Lili |
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| Abstract: | Betulinic acid and 2,3-hydroxyl betulinic acid were lupine-type tings Ttiterpenoid compounds, They had wide range of pharmacological activity, the anti-tumor effect has been of great concern in recent years. At presem betulinic acid and 2,3 -hydroxyl betulinic acid anti-tumor effect studies in home and abroad show that betulinic acid and 2,3-hydroxyl betulinic acid can inhibit tumor cell proliferation, transfer, induced differentiation and apoptosis of tumor cells, thus played the role of anti-tumor action. |
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| Keywords: | Betulinic acid 2,3-hydroxyl betulinic acid Anti-tumor |
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