| 小柴胡汤及其与青蒿素配伍的免疫学作用研究 |
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| 引用本文： | 王金华,叶祖光,薛宝云,戴宝强,肖永庆,杨庆,刘晓宏,李泽琳,屠国瑞.小柴胡汤及其与青蒿素配伍的免疫学作用研究[J].中国实验方剂学杂志,1995,1(1):28-33. |
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| 作者姓名： | 王金华 叶祖光 薛宝云 戴宝强 肖永庆 杨庆 刘晓宏 李泽琳 屠国瑞 |
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| 作者单位： | 中国中医研究院中药研究所 |
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| 基金项目： | 93－95国家自然科学基金 |
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| 摘 要： | 以伯氏疟原虫感染小鼠为实验模型研究了小柴胡汤、小柴胡汤与青蒿素（QHS）配伍用药的免疫学作用。研究结果表明：小柴胡汤或小柴胡汤与QHS合并用药均可显著提高疟疾小鼠的体液免疫、非特异性免疫、红细胞免疫的能力。对Con A诱导的淋巴母细胞转化有显著的免疫抑制作用。
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| 关 键 词： | 小柴胡汤 青蒿素 红细胞免疫 中药配伍 疟疾 免疫功能 淋巴细胞 免疫学 |
Immunological Effects of Xiaochaihu Decoction and Its Combination with Artemisinin in Mice Infected with Plasmodium berghei |
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| Wang Jinhu,Ye Zuguang,Xue Baoyun,Dai Baoqiang,Xiao Yongqing,Yang Qing,Liu Xiaohong,Li Zelin,and Tu Guorui.Immunological Effects of Xiaochaihu Decoction and Its Combination with Artemisinin in Mice Infected with Plasmodium berghei[J].China Journal of Experimental Traditional Medical Formulae,1995,1(1):28-33. |
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| Authors: | Wang Jinhu Ye Zuguang Xue Baoyun Dai Baoqiang Xiao Yongqing Yang Qing Liu Xiaohong Li Zelin and Tu Guorui |
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| Institution: | Institute of Chinese materia Medica,China Academy of Traditional Chinese Medicine,Beijing,100700 |
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| Abstract: | Effects of Xiaochaihu decoction alone and its combination with artemisinin (QHS) on immunological functions were studied in the mice infected with Plasmodium, berghei. The data obtained in this study demonstrated that Xiaochaihu decoction and its combination with QHS exhibited significant immunostimulation on humoral, nonspecific and red cell immunities. However, the con A-induced lymphoblastic transformation was remarkably depressed by the decoction and its combination. |
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| Keywords: | Xiaochaihu decoction artemisinin red cell immunity |
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