类风湿性关节炎与肺间质性病变

目的：探讨类风湿性关节炎（RA）患发生肺间质性病变（ILD）的相关性及其危险因素。方法：对30例类风湿性关节炎X线有间质性肺病变的患，和30例类风湿性关节炎无肺间质性病变的患进行回顾性分析。结果：类风湿性因子（RF）滴度超过1：60容易发生间质性肺病变（P＜0．05），肺间质病变严重程度与类风湿因子滴度呈正相关（P＜0．05），吸烟也加重肺间质性病变（P＜0．05），结论：类风湿性因子滴度越高，发生间质性肺病变的危险性越大，临床出现症状的时间越短，X线上表现亦越严重，病程，吸烟也是影响肺间质性病变的危险因素。

Correlation between rheumatoid arthritis and interstiteal lung disease

Objective To find out the corelation between RA and ILD,and the dangerous factors of RA patients who developed ILD?Method Retrospective analysis was performed in 60 RA patients,30 with x-ray proved ILD and 30 with x-ray proved no ILD?Result The patients whose RF titer is more than 1:640 are easily to develop ILD(P<0.05).The severity of ILD showed positive correlation with the titer of RF(P<0.05)?Cigarretting made ILD more severe(P<0.05).Conclusion Patients which higher titer of RF is likely to develop ILD?The patients who's symptoms occurred earlier,have a worse manifestation of x-ray ?Disease course and cigarretting are also dangerous factors that influence the development of ILD?