Electrocardiographic features in a patient with the coexistence of long QT syndrome and coronary vasospasm |
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| Authors: | Tanaka Yasuaki Nishizaki Mitsuhiro Yamawake Noriyoshi Sakurada Harumizu Hiraoka Masayasu |
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| Affiliation: | From the Department of Cardiology, Yokohama Minami Kyosai Hospital, Kanagawa, Yokohama, Japan;;Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan;;and Tokyo Medical and Dental University, Tokyo, Japan |
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| Abstract: | A 20-year-old woman suffered from cardiopulmonary arrest due to ventricular fibrillation. The electrocardiogram after resuscitation showed prolonged QTc interval with bifid T wave. On the third hospital day, the QTc interval and the T-wave changes improved. However, the QTc interval was distinctively prolonged after administration of epinephrine, oral glucose load, and intracoronary acetylcholine (Ach) into the left coronary artery. Moreover, an injection of Ach into the right coronary artery provoked severe coronary spasm. This is a case of the coexistence of long QT syndrome (LQTS) and coronary vasospasm, which may give an important clinical implication for the treatment of LQTS. |
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| Keywords: | long QT vasospastic angina coronary vasospasm VF sudden cardiac death ion channel acetylcholine epinephrine glucose insulin ICD |
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