Follicular Lymphoma with Extensive Gastrointestinal Tract Involvement: Follow-up by Capsule Endoscopy |
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| Authors: | Boris Sapoznikov Sarah Morgenstern Pia Raanani Adina Aviram Esther Rabizadeh Miron Prokocimer Yaron Niv |
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| Institution: | (1) Department of Gastroenterology, Rabin Medical Center, Tel Aviv University, Beilinson Campus, Petah Tiqwa, 49100, Israel;(2) Department of Pathology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;(3) Hematology Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;(4) Department of Hematology Laboratory, Rabin Medical Center, Beilinson Campus, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Felsenstein Research Center, Tel Aviv, Israel |
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| Abstract: | Follicular lymphoma with gastrointestinal tract involvement is rare. We describe the case of a young woman with follicular
lymphoma with multiple nodular lesions involving segments of the proximal jejunum and terminal ileum. The presenting symptom
was chronic diarrhea. The diagnosis was made by endoscopy with histologic examination of the mucosal lesions of the proximal
and distal small intestine, immunohistochemical staining, and molecular analysis. The initial spread and pattern of the small
bowel involvement, as well as treatment response, were evaluated by videocapsule endoscopy. The application of molecular analysis
along with immunophenotypic evaluation has made it possible to precisely diagnose follicular lymphoma. In the present case,
the use of capsule endoscopy improved the evaluation of the extent of small bowel involvement prior to and following treatment. |
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