| 原发性高血压患者红细胞膜Ca~(2+)—ATP酶活性的初步观察 |
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| 引用本文： | 何士大,于仲元,张叔诚,刘成立,徐宝钢,汪家瑞.原发性高血压患者红细胞膜Ca~(2+)—ATP酶活性的初步观察[J].首都医学院学报,1987,8(4):283-285. |
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| 作者姓名： | 何士大 于仲元 张叔诚 刘成立 徐宝钢 汪家瑞 |
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| 作者单位： | 首都医学院宣武医院心血管病研究室高血压实验室，首都医学院宣武医院心血管病研究室高血压实验室，首都医学院宣武医院心血管病研究室高血压实验室，首都医学院宣武医院检验科，首都医学院宣武医院心血管病研究室高血压实验室，首都医学院宣武医院心血管病研究室高血压实验室 指导教授 |
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| 摘 要： | 细胞膜 Ca~(2+)—ATP 酶对细胞内 Ca~(2+)转运发挥泵的作用。本文观察了20例原发性高血压患者红细胞膜 Ca~(2+)-ATP 酶活性并与正常人比较,发现该酶话性明显低于正常人,提示高血压患者依赖 ATP 的 Ca~(2+)转运能力降低。并同时观察到高血压患者尿 Ca~(2+)排出量与正常人比较明显增加。
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| 关 键 词： | 原发性高血压 红细胞膜 钙-ATP酶 |
The Preliminary Observation on the Activity of the Erythrocyte Membrane Ca2+ ATPase of Essential Hypertension Patients |
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| He Shida Hypertension Lab,Cardiovascular Research Lab Xuanwu Hospital,Capital Institute of Medicine.The Preliminary Observation on the Activity of the Erythrocyte Membrane Ca2+ ATPase of Essential Hypertension Patients[J].Journal of Capital University of Medical Sciences,1987,8(4):283-285. |
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| Authors: | He Shida Hypertension Lab Cardiovascular Research Lab Xuanwu Hospital Capital Institute of Medicine |
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| Institution: | Hypertension Lab, Cardiovascular Research Lab Xuanwu Hospital, Capital Institute of Medicine |
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| Abstract: | The membrane Ca2+-ATPase has the function as the pump to transport the intracelluar Ca2+. This work observed the activity of thc erythrocytes membrane of 20 hypertension patients and 20 normal subjects.The results have showed that hypertension patients have the lower activity of erythrocytes membrane Ca2+-ATPase than the normal subjects。The urine Ca2+ excretion of hypertension patients is increaed significantly than the normal group. |
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| Keywords: | essential hypertension erythrocyte membrane Ca~(2+)-ATPase |
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