血清抑制素-A水平与异位妊娠的相关性研究

目的探讨异位妊娠患者血清中抑制素-A(INH-A)的水平变化及临床意义。方法采用全自动化学发光免疫分析(CLIA)法对异位妊娠50例(观察组),正常孕妇50例(对照组)血清中INH-A、β-人绒毛膜促性腺激素(β-HCG)及孕酮水平进行检测。结果与对照组相比,观察组血清中INH-A(3.6±1.4)、β-HCG(308.5±57.9)、孕酮(29.8±9.4)的水平均明显降低,差异有统计学意义(P<0.01)。结论血清INH-A对异位妊娠的早期诊断和治疗起到积极的辅助作用。

A study on correlation between the serum levels of inhibin-A and the ectopic pregnancy

Objective To investigate the serum levels and clinical significance of INH-A in ectopic pregnancy by chemiluminescence immune assay （CLIA）. Methods The serum levels of INH-A, β-HCG and Prog in 50 patients with ectopic pregnancy （the study group） and 50 normal pregnant women （the control group） were detected by CLIA. Results Compared with the control group, the serum levels of INH-A （3.6±1.4）, β-HCG （ 308.5±57.9） and Prog （29.8±9.4） were significantly decressed, the difference was significant （P 〈 0.01 ）. Conclusion INH-A plays an important role in sustaining the normal early pregnancy, and predicts the early pregnancy outcome effectively. It plays an active supporting role in the early diagnosis and treatment of ectopic pregnancy.