前列腺突入膀胱距离及逼尿肌厚度与膀胱出口梗阻的关系探讨

目的探讨前列腺突入膀胱距离(intravesical prostatic protrusion,IPP)及逼尿肌厚度(de-strusor wall thickness,DWT)与良性前列腺增生(benign prostatic hyperplasia,BPH)所致膀胱出口梗阻(bladder outlet obstruction,BOO)的关系,旨在寻找一种简单、非侵入性诊断的方法。方法选择前列腺增生有下尿路症状患者200例,予经腹超声检查及尿流动力学检查,测量参数包括:IPP、DWT、残余尿量(post-void residual urine,PVR)、前列腺体积(prostate volume,PV)、尿流动力学Schaefer分级;对数据进行统计分析并绘制相应ROC曲线。结果 IPP、DWT、PV与Schaefer分级相关相关系数(r)分别为0.73、0.56、0.23,P值均<0.01];PVR与Schaefer分级无关;IPP、DWT、PV的ROC曲线下面积分别为0.80、0.84、0.60。结论经腹超声测量DWT、IPP可以预测前列腺增生患者BOO程度,是一种简单、无创、有效的评估方法。

Correlation of intravesical prostatic protrusion and detrusor wall thickness with bladder outlet obstruction

Objective To investigate the correlation of intravesical prostatic protrusion （IPP） and de- trusor wall thickness （DWT） with bladder outlet obstruction （BOO） in patients with benign prostatic hyperpla- sia （BPH） , and to find a simple and noninvasive method to diagnose BOO. Methods A total of 200 men with lower urinary tract symptoms （LUTS） due to BPH were prospectively enrolled. The initial evaluation included DWT, IPP, post-void residual urine （ PVR）, prostate volume （ PV）, Schaefer obstruction class. These data were analyzed with statistic and produced a ROC curve. Results There are significant correlation between IPP, DWT and PV with the Schaefer obstruction class （ r = 0. 73 ,0. 38,0. 23 , respectively ;P 〈 0.01 ）. There were no corre- lation between PVR and the Schaefer obstruction class. The AUC for IPP, DWT,PV was 0. 80 , 0. 84 , 0. 60 , respectively. Conclusion Trans-abdominal ultrasound of IPP and DWT can be used to predict patients with BOO due to BPD, and it is a simple, noninvasive, and effective method.