| 长春地辛联合化疗治疗非小细胞肺癌 |
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| 引用本文： | 赵文英,彭玉珍,吴跃文.长春地辛联合化疗治疗非小细胞肺癌[J].皖南医学院学报,2001,20(2):107-109. |
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| 作者姓名： | 赵文英 彭玉珍 吴跃文 |
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| 作者单位： | 附属弋矶山医院肿瘤内科 |
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| 摘 要： | 目的 探讨 ＭＶＰ方案对非小细胞肺癌的治疗价值。方法 ３４例患者采用 ＭＶＰ（ ＭＭＣ＋ ＶＤＳ＋ ＤＤＰ）方案治疗。结果 ＣＲ３例，ＰＲ１８例，ＮＣ１０例，ＰＤ ３例，总有效率 ６１．８％（２１／３４）。分析诸因素对疗效的影响，无显著性差异（Ｐ＞０．０５）。毒性反应主要是骨髓抑制及消化道反应。结论ＭＶＰ方案治疗晚期ＮＳＣＬＣ有较好疗效，毒副反应轻微，可作为一线方案。
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| 关 键 词： | 非小细胞肺癌 长春地辛 丝裂霉素 顺铂 联合化疗 |
| 修稿时间： | 1999年9月3日 |
Vindesine Combined-chemotherapy in the Treatment of Non-Small Cell Lung Cancer |
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| Zhao Wenying,Peng Yuzhen,Wu Yuewen.Vindesine Combined-chemotherapy in the Treatment of Non-Small Cell Lung Cancer[J].Acta Academiae Medicinae Wannan,2001,20(2):107-109. |
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| Authors: | Zhao Wenying Peng Yuzhen Wu Yuewen |
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| Abstract: | Objective :To explore the therapeutic value of MVP regimen for the treatment of non-small cell lung cancer (NSCLC). Methods 34 cases were treated with MVP (MMC VDS DDP) regimen. Results 3 patients showed complete response; 18 patients showed partial repsonse; 10 patients showed no change; 3 patients showed progressive disease. The overall response rate was 61. 8 % (21/34). The major toxic effects were myelosuppression and gastrointestinal tract reaction. Conclusion MVP is an effective regimen in the patients with advanced non-small cell lung cancer,and due to mild toxicity may be used as a choice regimen. |
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| Keywords: | non-small cell lung cancer vindesine mitomycin cisplation combined chemotherapy |
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