乌灵胶囊联合苯磺酸氨氯地平治疗高血压病伴焦虑症

目的:探讨乌灵胶囊联合苯磺酸氨氯地平治疗对高血压病伴焦虑症患者的临床效果。方法:将90例高血压病伴有焦虑症状的患者,随机分为三组各30例,A组予以氨氯地平5mg,1次/d降压治疗;B组加用帕罗西汀20mg,1次/d;C组加用乌灵胶囊3粒,3次/d。4周后观察各组降压有效率及药物不良反应。结果:降压有效率A组为53.3%,B组为83.3%,C组为80.0%,B、C两组与A组比较,差异有统计学意义(P0.05);C组低于B组,但差异无统计学意义(P0.05);B组出现恶心、食欲减退、口干、失眠等,C组无不良反应。结论:对高血压病伴焦虑症状的患者,氨氯地平联合应用帕罗西汀或乌灵胶囊能明显提高疗效,乌灵胶囊副作用少,易于患者耐受。

A clinical research on treating HBP with anxiety disorders with Wuling capsule combined with amlodipine besylate

Objective：To investigate clinical effects of Wuling capsule combined with amlodipine besylate.Methods：To divide 90 patients into three groups（30 for each）,A group took amlodipine besylate 5mg/d;B group took paroxetine 20mg/d more;C group took 3 Wuling capsules/d more;and side effects and efficacy of relieving HBP were compared after 4 weeks.Result：The efficacy of relieving HBP in A was 53.3%;it is 83.3% in B;it is 80.0% in C.The difference for B and C compared with A was significant（P0.05）,C is low to B but no significance;and there was Nausea,loss of appetite,dry mouth,insomnia,etc.in B;there was no side effects in C.Conclusion：For patients with HBP and anxiety,Wuling capsule combined with amlodipine besylate is much better;and Wuling capsules has little side effects.