Effect of graft size matching on pediatric living‐donor liver transplantation at a single center |
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| Authors: | Jun‐Jie Li Cai‐Hua Zu Shi‐Peng Li Wei Gao Zhong‐Yang Shen Jin‐Zhen Cai |
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| Affiliation: | 1. Department of Liver Transplantion, Oriental Organ Transplant Center, Tianjin First Central Hospital, Tianjin, China;2. Department of Gastroenterology, Zhengzhou Yi He Hospital Affiliated to Henan University, Zhengzhou, China;3. Department of General Surgery, Jiaozuo People's Hospital, Xinxiang Medical University, Jiaozuo, China |
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| Abstract: | We retrospectively analyzed 252 patients with end‐stage liver disease who had undergone LDLT from January 2009 to September 2015. Of these, 25 had a GRWR of <2.0% (Group A), 204 had a GRWR of ≥2.0% or <4.0% (Group B), and 23 had a GRWR ≥4.0% (Group C). The three GRWR groups demonstrated similar characteristics, except for recipient age and recipient BMI. The overall 1‐, 2‐, and 3‐year graft survival rates were 95.1%, 93.5%, and 93.5%, respectively. However, among the three groups, graft survival rates at 1 year, 2 years, and 3 years were significantly different (P = .0009). Hepatic artery stenosis/thrombosis was more frequently observed in Group C than in Groups A and B (P = .001). Wound infection was also more frequently observed in Group C than in Group A and B (P = .002). However, intestinal fistula/bile leakage/biliary‐enteric anastomotic fistula was more frequently observed in Group A than in Groups B and C (P = .001). In addition, reoperation more frequently occurred in Group A and C than in Group B (P = .001). Recipients with a GRWR between 2.0% and 4.0% had significantly better graft survival rates. |
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| Keywords: | graft‐to‐recipient weight ratio living‐donor liver transplantation patient and graft survival rates pediatric |
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