| 桃仁提取液抑制巩膜瓣下小梁切除术后滤床纤维母细胞增殖的实验研究 |
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| 引用本文： | 汪素萍,方军,嵇训传,郑应昭.桃仁提取液抑制巩膜瓣下小梁切除术后滤床纤维母细胞增殖的实验研究[J].复旦学报(医学版),1993(1). |
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| 作者姓名： | 汪素萍 方军 嵇训传 郑应昭 |
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| 作者单位： | 上海医科大学眼耳鼻喉科医院眼科
(汪素萍，嵇训传)，上海医科大学基础医学院病理学教研室
(方军)，上海医科大学眼耳鼻喉科医院眼科(郑应昭) |
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| 摘 要： | 桃仁对经体外细胞培养中的纤维母细胞生长具有抑制作用,将其用于实验性小梁切除术的家兔动物模型上。发现它具有抑制炎症细胞及纤维母细胞增生的作用;局部应用无副反应。可能是一种防止抗青光眼滤过性手术后过度疤痕形成,促进功能性滤过泡形成的安全而有效的药物。
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| 关 键 词： | 桃仁提取液 纤维母细胞 抗青光眼滤过性手术 小梁切除术 |
EXPERIMENTAL RESEARCH OF EXTRACTUM SEMEN PERSICAE IN INHIBITING FIBROBLASTIC PROLIFERATION AFTER TRABECULECTOMY SURGERY |
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| Wang Su-Ping,Fang Jun,Ji Xun-Ohuan,Zheng Ying-Zhao.EXPERIMENTAL RESEARCH OF EXTRACTUM SEMEN PERSICAE IN INHIBITING FIBROBLASTIC PROLIFERATION AFTER TRABECULECTOMY SURGERY[J].Fudan University Journal of Medical Sciences,1993(1). |
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| Authors: | Wang Su-Ping Fang Jun Ji Xun-Ohuan Zheng Ying-Zhao |
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| Abstract: | Based on the finding that extractum semen persicae (ESP) could inhibit the fibroblasts growth in the culture medium. ESP was used locally in the animal model of experimental trabeculectomy. It was proved once again that ESP had the potential of inhibiting inflammatory cells reaction and fibroblastio proliferation with no side effects.We postulated that ESP may be a promising and effective agent in prevent from excessive scarring and promotion of filtering bulb formation following filtering operation. |
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| Keywords: | extratum semen persicae fibroblasts antiglaueomatous filtering surgery trabeouleotomy |
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