A messenger at the door: cytomegalovirus retinitis in myeloma patients with progressive disease |
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| Authors: | BW Teh AS Khot SJ Harrison HM Prince MA Slavin |
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| Institution: | 1. Department of Infectious Diseases and Infection Control, Peter MacCallum Cancer Centre, , East Melbourne, Victoria, Australia;2. Department of Haematology, Peter MacCallum Cancer Centre, , East Melbourne, Victoria, Australia;3. Sir Peter MacCallum Department of Oncology, University of Melbourne, , Parkville, Victoria, Australia;4. Victorian Infectious Diseases Service, Royal Melbourne Hospital, , Parkville, Victoria, Australia |
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| Abstract: | Cytomegalovirus (CMV) retinitis is an uncommon manifestation of CMV disease and is a marker of severe and profound immunosuppression in human immunodeficiency virus‐positive patients. Here, we describe 2 cases of CMV retinitis in myeloma patients with progressive disease, following autologous stem cell transplantation and immunomodulatory therapy for myeloma. To our knowledge, this is the first report of CMV retinitis in this patient population. This report illustrates the need for close monitoring of relapsed and refractory myeloma patients for new presentations of opportunistic infections secondary to severe immunosuppression. |
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| Keywords: | myeloma
CMV
retinitis |
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