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Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy
Authors:Gang Shi  Qianmei Yang  Yujing Zhang  Qingyuan Jiang  Yi Lin  Shenshen Yang  Huiling Wang  Lin Cheng  Xin Zhang  Yimin Li  Qingnan Wang  Yi Liu  Qin Wang  Hantao Zhang  Xiaolan Su  Lei Dai  Lei Liu  Shuang Zhang  Hongxin Deng
Affiliation:1. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan 610041, China;2. Department of Obstetrics, Sichuan Provincial Hospital for Women and Children, Chengdu, China;3. Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China;4. Innovent Biologics, Inc., Suzhou, Jiangsu, China
Abstract:
Keywords:combination immunotherapy  tumor microenvironment  anti-PD-1 antibody  oncolytic virus  CSF-1R inhibitor
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