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抗精子抗体对不孕不育和流产患者的影响
引用本文:杨冬梅,赵丽红. 抗精子抗体对不孕不育和流产患者的影响[J]. 中国实验诊断学, 2007, 11(10): 1370-1371
作者姓名:杨冬梅  赵丽红
作者单位:首都医科大学附属北京妇产医院,检验中心,北京,100026
摘    要:目的为探讨抗精子抗体(AsAb)在不孕不育流产中的作用。方法采用快速抗精子抗体ELISA试剂盒检测不孕不育流产患者AsAb。结果在不孕不育患者中AsAb阳性率女性明显高于男性,其中,原发不孕不育患者中男性阳性率为12.59%(34/270),女性检出率29.62%(32/108);继发不育患者中男性阳性率为21.42%(3/14),女性检出率37.5%(6/16);多次流产患者中,男性检出率18.51%(5/27),女性为31.25%(5/16)。与对照组比较(P<0.05),具有显著性差异。结论AsAb检测对不孕不育的诊断具有重要意义。

关 键 词:不孕不育  抗精子抗体  免疫性
文章编号:1007-4287(2007)10-1370-02
修稿时间:2007-01-12

Effect of Anti-sperm Antibodies on Infertile Sterile and Miscarriage Patients
YANG Dong-mei,ZHAO Li-hong. Effect of Anti-sperm Antibodies on Infertile Sterile and Miscarriage Patients[J]. Chinese Journal of Laboratory Diagnosis, 2007, 11(10): 1370-1371
Authors:YANG Dong-mei  ZHAO Li-hong
Affiliation:Laboratory of Beijing Obstetrical and Gynecological Hospital, Capital University of Medical Sciences Beijing 100026, P. R. China
Abstract:Objective To investigate the effect of anti-sperm antibodies(AsAb) on infertile sterile and miscarriage patient.Methods We examine infertile sterile and miscarriage patient's AsAb with the method of fast anti-sperm antibody ELISA reagent box.Results Women AsAb's positive rate is obviously higher than men among infertile sterile patient.Men AsAb's positive rate is 12.59%(34/270),and women's is 29.62%(32/108)among primary infertile sterile patients,and men's is 21.42%(3/14),while women's is 37.5%(6/16) among secondary infertile sterile patients.Among the patients who have aborted more than one time,men AsAb's positive rate is 19.51%(5/27),and women's is 31.25%(5/16).Compared with contrasting groups,there are significance differences(P<0.05).Conclusion It is significant to infertile sterile diagnosis to examine AsAb.
Keywords:infertile sterile  AsAb  immunity
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