| 维生素C对柯萨奇B_3病毒感染的心肌细胞的保护作用研究 |
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| 引用本文： | 张福明,王相峰,张淑琴. 维生素C对柯萨奇B_3病毒感染的心肌细胞的保护作用研究[J]. 吉林大学学报(医学版), 1997, 0(4) |
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| 作者姓名： | 张福明 王相峰 张淑琴 |
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| 作者单位： | 白求恩医大第一临床学院 |
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| 摘 要： | 观察维生素Ｃ对柯萨奇Ｂ３（ＣＶＢ３）病毒的复制和对病毒感染心肌细胞的影响，结果表明：维生素Ｃ（ＶｉｔＣ）对ＣＶＢ３感染的心肌细胞具有保护作用，加ＶｉｔＣ培养２４ｈ后，随时间延长，保护作用越来越明显（Ｐ＜０．０５）；实验结果还表明：ＶｉｔＣ在细胞外并无直接灭活病毒作用，而是作用于细胞，影响病毒的复制，从而使心肌细胞得到保护。
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| 关 键 词： | 维生素C 柯萨奇B_3病毒 心肌细胞 |
Protective effect of VC on myocardial cells infected by Coxsackie virus B 3 |
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| Abstract: | In this paper,we studied the effect of VC on the reproduction of CVB 3 and the activity of myocardial cells which were infected by the viruses.The results showed that vitamine C (VC) protected myocardial cells from virus infection .The protection of VC to the cells incrased with cultured period ( P <0 05).Therefore,the mechanism of the protection was probably that VC affected virus proliferation by the cells,and the myocardial cells were prevented from virus infection. |
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| Keywords: | Vitamine C Coxsackie virus B 3 Myocardial cell |
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