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大鼠蓝斑核区内源性神经降压素对迷走—加压反应的影响
引用本文:徐珞,陈家津. 大鼠蓝斑核区内源性神经降压素对迷走—加压反应的影响[J]. 青岛大学医学院学报, 1989, 25(4): 304-306
作者姓名:徐珞  陈家津
作者单位:青岛医学院生理学教研室(徐珞),青岛医学院生理学教研室(陈家津)
摘    要:用放射免疫分析及核团微量注射法,探讨了大鼠蓝斑核区内源性神经降压素对迷走-加压反应的影响。实验结果,电刺激双侧颈迷走神经向中端,蓝斑核区神经降压素免疫活性物的含量明显增高(P<0.05);蓝斑核区注入抗神经降压素血清,迷走-加压反应明显加强(P<0.01)。提示大鼠蓝斑核区内源性神经降压素对迷走-加压反应有抑制作用。

关 键 词:迷走神经  放射免疫测定  微量注射  蓝斑  神经降压素  大鼠

EFFECT OF ENDOGENOUS NEUROTENSIN ON VAGUS-PRESSOR RESPONSE IN RAT NUCLEUS LOCUS COERULEUS
Xu Luo Chen Jiajin. EFFECT OF ENDOGENOUS NEUROTENSIN ON VAGUS-PRESSOR RESPONSE IN RAT NUCLEUS LOCUS COERULEUS[J]. Acta Academiae Medicinae Qingdao Universitatis, 1989, 25(4): 304-306
Authors:Xu Luo Chen Jiajin
Affiliation:Xu Luo Chen Jiajin Department of Physiology
Abstract:By means of radioimmunoassay and nucleus microinjections we studied the effectof endogenous neurotensin on vagus.pressor response in rat nucleus locus coeruleusThe results are as follows:the content of the neurotensin-immunoreaction wasobviously increased near the central end of the vagus nerve stimulation (P<0.05)The vagus.pressor reaction was significantly potentiated by antineurotensin seruminjection to nucleus locus coeruleus (P<0.01).The results indicate that endogenousneurotensin in rat nucleus locus coeruleus inhibits vagus-pressor response.
Keywords:Vagus Nerve  Radioimmunoassay  Microinjections  Locus coeruleus  Rats
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