| 羊传染性脓疱病毒抗干扰素基因(VIR)研究进展 |
| |
| 引用本文： | 王玲玲,刘永杰,郑海学,张克山,刘湘涛. 羊传染性脓疱病毒抗干扰素基因(VIR)研究进展[J]. 中国人兽共患病杂志, 2015, 31(12): 1181-1184. DOI: 10.3969/j.issn.1002-2694.2015.12.019 |
| |
| 作者姓名： | 王玲玲 刘永杰 郑海学 张克山 刘湘涛 |
| |
| 作者单位： | 中国农业科学院兰州兽医研究所,家畜疫病病原生物学国家重点实验室,国家口蹄疫参考实验室,兰州 730046 |
| |
| 基金项目： | 国家自然科学基金(No; NSFC-31201914),中国博士后科学基金(No.2013M530683)和 国家现代肉羊产业技术体系(No; CARS-39)联合资助 |
| |
| 摘 要： | 羊传染性脓疱病毒(ORFV)是痘病毒科副痘病毒属的成员之一,引起严重的人兽共患传染病。该病毒基因组全长约134~139 kb,编码130多个蛋白,抗干扰素基因是ORFV编码的具有拮抗宿主干扰素功能的蛋白,在ORFV突破宿主免疫屏障过程中有重要作用。本文就抗干扰素基因的研究进展作一综述。
|
| 关 键 词： | 羊传染性脓疱病毒 VIR基因 研究进展 |
| 收稿时间： | 2015-04-01 |
Progress on virus interferon resistance gene encoded by Orf virus |
| |
| WANG Ling-ling,LIU Yong-jie,ZHENG Hai-xue,ZHANG Ke-shan,LIU Xiang-tao. Progress on virus interferon resistance gene encoded by Orf virus[J]. Chinese Journal of Zoonoses, 2015, 31(12): 1181-1184. DOI: 10.3969/j.issn.1002-2694.2015.12.019 |
| |
| Authors: | WANG Ling-ling LIU Yong-jie ZHENG Hai-xue ZHANG Ke-shan LIU Xiang-tao |
| |
| Affiliation: | Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou 730046, China |
| |
| Abstract: | Orf virus (ORFV) is one of the prototype species of the Parapoxvirus genus of the Poxviridae family and causes serious zoonotic infectious disease. The genome of ORFV ranges in size from 134 kb to 139 kb, containing about 130 genes. VIR encoded by ORFV is a protein involved in interferon resistance and plays an important role in the progress of ORFV breakthrough host immune barrier. This paper reviewed the status and research progress of VIR. |
| |
| Keywords: | orf virus VIR gene research progress |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国人兽共患病杂志》浏览原始摘要信息 |
|
点击此处可从《中国人兽共患病杂志》下载全文 |
