Clinical and radiographic evaluation of platelet-rich fibrin for revascularization of necrotic immature permanent teeth: A controlled clinical trial |
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| Affiliation: | 1. Faculty of Dentistry, Thamar University, Dhamar, Yemen;2. Faculty of Dentistry, Mansoura University, Mansoura, Egypt;1. Department of Pediatric & Preventive Dentistry, JSS Dental College & Hospital, JSS Academy of Higher Education & Research, Mysuru, India;2. Department of Oral Pathology & Microbiology, JSS Dental College & Hospital, JSS Academy of Higher Education & Research, Mysuru, India;1. University of the West Indies, St. Augustine, Trinidad and Tobago;2. University of Dundee, UK;1. Department of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil;2. School of Health Sciences, Positivo University, Curitiba, Brazil;3. School of Health Science, University of Joinville, Joinville, Santa Catarina, Brazil;1. The Committee of Emphasis Study, Japanese Association for Dental Science, Tokyo, Japan;2. Division of Rehabilitation for Speech and Swallowing Disorders, The Nippon Dental University, Tama Oral Rehabilitation Clinic, Tokyo, Japan;3. Division of Pediatric Dentistry, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Kanagawa, Japan;4. Department of Pediatric Dentistry, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan;5. Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Nagano, Japan;6. Department of Pediatrics and Laboratory Medicine, Tokyo Metropolitan Fuchu Medical Center for the Disabled, Tokyo, Japan;7. Nakajima Dental Clinic, Kanagawa, Japan;8. Japan Dental Association, Tokyo, Japan;9. Faculty of Human Sciences, Waseda University, Tokyo, Japan;10. Department of Special Needs and Geriatric Dentistry, Kyushu Dental University, Fukuoka, Japan;11. Department of Pediatric Dentistry, Kagoshima University Hospital, Kagoshima, Japan;12. Japanese Association for Dental Science, Tokyo, Japan;1. Section of Pediatric Dentistry, Department of Oral Growth and Development, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0193, Japan;2. Section of Functional Structure, Department of Morphological Biology, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0193, Japan;3. Kato Dental Office for Children, Sawara-ku, Fukuoka, Japan |
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| Abstract: | BackgroundIdeal management of necrotic immature permanent teeth to close the blunderbuss apical opening still of challenge and debate.Objectiveclinical and radiographic evaluation of platelet rich fibrin (PRF) for revascularization of necrotic immature permanent teeth.Method28 single-rooted necrotic immature permanent teeth from 28 children (7–13 years old) assigned into two main groups (contaminated and uncontaminated). Teeth of each group divided randomly into two subgroups according to type of treatment; PRF subgroup (experimental) and calcium hydroxide apexification subgroup (control). Clinical and radiographic evaluations assessed at baseline, 3, 6, and 9 months.Resultsall subgroups showed clinical success of 100%. Radiographic results presented a significant difference in all intervals regarding root length, diameter of apical foramen and radiographic root area (RRA) in PRF subgroups. Regarding root length, significant difference was for PRF subgroup at 3rd interval in group I. Diameter of apical foramen showed significant differences for PRF subgroups at 2nd and 3rd intervals. RRA revealed significant differences for PRF subgroups in both groups at 2nd and 3rd intervals.Conclusionsplatelet-rich fibrin revascularization and calcium hydroxide apexification were successful clinically. Radiographically, platelet-rich fibrin showed significant quantitative measurements than calcium hydroxide apexification regarding all parameters. |
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| Keywords: | Platelet-rich fibrin Immature teeth Revascularization Calcium hydroxide |
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