Interstitial pneumonia developed after combination chemotherapy with (CDDP, VDS, MMC) and radiotherapy

Reported is a case of interstitial pneumonia that developed after CDDP, VDS, and MMC combination chemotherapy and radiotherapy. The patient, a 68-year-old male, had received chemotherapy three times, beginning with CDDP + VDS, followed by CDDP, VDS, and MMC, in that sequence, after which he was given radiotherapy. The interstitial pneumonia developed one day after a dose of 54 Gy. It is felt that MMC played the leading role and the radiation the inducing role in the development of his interstitial pneumonia.