类风湿关节炎患者合并甲状腺疾病的临床分析

目的探讨类风湿关节炎（RA）患者合并甲状腺疾病的发生情况和严重程度。方法回顾性研究分析我院123例RA患者,根据甲状腺功能情况分为甲状腺功能正常组和异常组,分别作为对照组和观察组,确定RA评分,并测定两组患者的甲状腺功能、TPOAb、TGAb,进行统计学分析。结果 123例RA患者中有28例合并甲状腺功能异常,发生率22.8%。观察组RA评分和TPOAb、TGAb阳性率均高于对照组,且RA评分与TPOAb、TGAb呈正相关。RA评分与甲状腺功能无相关性。结论 RA合并甲状腺功能异常应引起广大医务工作者的重视,特别是重视对RA患者完善甲状腺功能和相关抗体的筛查,从而尽早采取更积极的治疗,改善预后。

The Clinical Analysis of Rheumatoid Arthritis Incorporate with Thyroid Disease.

Objective To inquiry into the Incidence and severity of rheumatoid arthritis incorporate with thyroid disease. Method The retrospective analysis of 123 patients, were divided into the normal group and abnormal group according to thyroid function respectively, as the observation group and the control group. RA score ,thyroid function ,TPOAb and TGAb of the 123 patients were confirmed and analyzed statistically. Results Among the 123 RA patients, 28 cases with abnormal thyroid function, the incidence was 22. 8%. The observation group RA score and the positive rate of TPOAh,TGAb was higher than that of the control group, RA was positively correlated with the TPOAb and TGAb score, No correlation between RA score and thyroid function. Conclusion RA patients with abnormal thyroid function should cause the attention of medical workers, especially pay attention to patients with RA improve screening thyroid function and antibodies, so as soon as possible to take more aggressive treatment, improve the prognosis.