异时性多原发性结直肠癌15例临床分析

目的 探讨异时性多原发性结直肠癌（MCC）的临床特点、诊断及治疗。方法 回顾分析2000年至2013年收治的15例异时性多原发性结直肠癌患者的临床资料,分析异时性多原发性结直肠癌的发病状况,诊断治疗及预后。结果异时性多发性结直肠癌病例占同期所有收治结直肠癌的1.26%（15/1189）,占多发性结直肠癌的36.59%（15/43）,平均间隔时间为3.2年,均为肠镜随访发现,15例首次均行手术切除,再发癌以Dukes B期多见。结论 异时性多原发性结直肠癌临床病理学特点突出,应重视术后肠镜复查,早期发现,积极手术,提高患者生存率。

Clinical Analysis of 15 Cases with Metachronous Multiple Primary Colorectal Carcinoma

Objective To get a clearer understanding on the clinicopathological characteristics,the diagnosis and treatment of metachronous multiple primary colorectal carcinoma. Methods The clinical data of 13 patients with metachronous multi-ple primary colorectal carcinoma,treated in our hospital during 2005 to 2011,were retrospectively analyzed. Results The percentage of patients with metachronous multiple primary colorectal carcinoma was 1. 36%（ 13/955 ） and the average interval was 2. 8 years. All cases were diagnosed by colonoscopy. Radical resection was performed on 10 patients,palliative resection on the other one. The second carcinoma most often happened at Dukes B stage. Conclusion Metachronous colorectal carcinoma has special clinical and pathological features. Colonoscopy is critical to its diagnosis. early detection、early diagnosis and early treatment can improve the prognosis.