Positive Result by Serology Indicates Active Helicobacter pylori Infection in Patients with Atrophic Gastritis |
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| Authors: | Arto Kokkola, Hilpi Rautelin, Pauli Puolakkainen, Pentti Sipponen, Martti F rkkil , Reijo Haapiainen, Timo U. Kosunen |
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| Affiliation: | Arto Kokkola, Hilpi Rautelin, Pauli Puolakkainen, Pentti Sipponen, Martti Färkkilä, Reijo Haapiainen, and Timo U. Kosunen |
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| Abstract: | Patients with atrophic corpus gastritis and elevated Helicobacter pylori antibody titers but 13C-urea breath test (13C-UBT) and histology results negative for H. pylori were randomized into eradication therapy or follow-up only. Antibody levels decreased significantly in six out of seven patients in the eradication group, while in the follow-up group, the titers declined in only one out of eight patients. In patients with atrophic corpus gastritis, positive serology results may indicate an ongoing infection in spite of negative 13C-UBT and histology results. |
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