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Merkel cell carcinoma and iodine-131 metaiodobenzylguanidine scan |
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| Authors: | Antonio Castagnoli Gianpaolo Biti Maria T. R. De Cristofaro Paolo Ferri Stefano M. Magrini Maria G. Papi Simonetta Bianchi |
| Affiliation: | (1) Dipartimento di Fisiopatologia Clinica, Universitá degli Studi, V.le Morgagni 85, I-50134 Firenze, Italy;(2) U.O. Medicina Nucleare USL 10D, Universitá degli Studi, V.le Morgagni 85, I-50134 Firenze, Italy;(3) U.O. Radioterapia USL 10D, Universitá degli Studi, V.le Morgagni 85, I-50134 Firenze, Italy;(4) Istituto di Anatomia Patologica, Universitá degli Studi, V.le Morgagni 85, I-50134 Firenze, Italy |
| Abstract: | Two cases of Merkel cell carcinoma, a neuroendocrine neoplasia of the skin, investigated with iodine-131 metaiodobenzylguanidine (131i-mIBG) scintigraphy, are reported. Uptake in the tumor was evident only in 1 case. The possible diagnostic and therapeutic role of 131I-mIBG in patients with this rare neoplasm is discussed.Offprint requests to: A. Castagnoli |
| Keywords: | Merkel cell carcinoma Neural crest tumors Radioiodinate metaiodobenzylguanidine Diagnosis Therapy |
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